24-02-2015
José J. G. Moura and Luísa B. Maia from UCIBIO, REQUIMTE, Biological Chemistry Laboratory (http://sites.fct.unl.pt/biologicalchemistryatfctunl) coordinate, in col. with Paul V. Bernhardt and Pablo J. Gonzalez, a Special Issue of Journal of Biological Inorganic Chemistry, on “Molybdenum and Tungsten Enzymes: from Biology to Chemistry and back”, March 2015 (http://link.springer.com/journal/775/20/2/page/1).
This special issue of JBIC was motivated by the 2013 Molybdenum & Tungsten Enzymes Conference, held in Sintra, Portugal. This conference series is special in that it brings together an extremely broad cross section of scientists from areas including Bioinorganic Chemistry, Enzymology, Microbiology, Biochemistry, Crystallography and Spectroscopy with a common interest in the structure, function and applications of Mo and W enzymes. Both Mo and W hold special places in Bioinorganic Chemistry, as they are the only elements of their respective (2nd and 3rd) rows of the transition series found in nature.
The issue focuses on the mononuclear molybdenum and tungsten-pterin-containing enzymes, including contributions from the nitrogenase field, where Mo is associated with Fe, in the FeMoco cluster.
A comprehensive account of the field is given, through the publication of several key mini-reviews, each summarizing the state-of-the-art knowledge and identifying outstanding questions and future directions. In addition, the issue includes a variety of original research articles spanning the entire Mo and W enzyme field.
